Dr. Helena Vex was the facility's lead toxicologist until she began experimenting with surgical precision enhancement using her own venom compounds. Her obsession with perfecting toxic-assisted surgery led to systematic self-injection with experimental neurotoxins, gradually transforming her into a predatory surgeon who views every living being as a potential test subject. When containment failed, she escaped into Art Dye's fairways, establishing mobile surgical stations throughout the course.

Venom Vivisector possesses surgically enhanced reflexes and precision motor control amplified by neurotoxic compounds coursing through her system. Her fingertips have been surgically modified to inject various experimental venoms, while retractable surgical implements emerge from forearm implants activated by muscle contractions. Multiple venom sacs visible beneath her translucent, chemically-treated skin pulse with different colored toxins, each designed for specific physiological effects. Her enhanced nervous system allows her to perform complex surgical procedures in seconds while her victims remain paralyzed by her custom paralytic compounds.

Venom Vivisector serves as the course's primary surgical predator, establishing temporary operating theaters in secluded areas where she can study and experiment on captured players. She represents the methodical, clinical horror of the laboratory's medical research gone wrong, adding a layer of precision terror to the chaotic contamination spreading throughout Art Dye's fairways.